Liver function tests are tests performed when a liver dysfunction is suspected. To know what does it consist of? What diseases can it reveal? What is the LFT test cost in Delhi, keep reading.
The designation "liver function tests" is somewhat misleading because most of these tests detect inflammation or damage to the liver; they do not actually explore the metabolic or secretory functions of liver bile. Such inflammation or lesions may be present even before the functions of the liver are affected. Liver function tests are blood tests that are a non-invasive way to check for liver disease (for example, hepatitis in a blood donation) and to measure the severity and progression of a disease of the liver and its response to treatment.
What is a hepatic blood test?
The hepatic blood test makes it possible to identify certain pathologies of the liver. Several elements are then assayed: hepatic enzymes (alanine aminotransferase, aspartate aminotransferase, gamma-glutamyl transferase, and alkaline phosphatase), bilirubin and albumin. The dosage of this protein makes it possible to evaluate the synthesis capacities of the liver.
- Laboratory analyses are generally effective for:
- Detect inflammation, lesions or dysfunction of the liver
- Assess the severity of a liver injury
- Monitor a person's progress in liver disease and response to treatment
- Specify the diagnosis
When is a full liver test prescribed?
Liver function tests may be requested to confirm an abnormality in liver function and to determine its origin. For example in case of jaundice, dark urine, in the presence of nausea, diarrhea or unexplained vomiting, clear or discolored stools, weight loss or even fatigue, a liver test is indicated. It also makes it possible to monitor the development of liver damage once the diagnosis has been made.
What is a liver test?
To carry out a hepatic assessment, it is necessary to take a blood test. From this, a determination of enzymes produced by the liver or specific to this organ is carried out. Here are the main ones:
- The transaminase (SGPT or ALT and SGOT or AST)
- Gamma-glutamyltranspeptidase ( Gamma-GT or GGT)
- The bilirubin
- The alkaline phosphatase (ALP)
- The prothrombin level
Disturbed liver balance: rate and causes
Although these indicators alone cannot confirm a particular pathology, certain dosages are however symptomatic of specific disorders.
The abnormally high bilirubin level may indicate cholestasis, pancreatitis, or pancreatic cancer. Hepatic failure is usually indicated by an abnormally low prothrombin level.
An increase in transaminases (ALAT and ASAT) shows the presence of cytolysis, corresponding to the destruction of liver cells during viral hepatitis, alcoholism, drug intoxication or even a vesicle problem biliary. Anyway, a precise interpretation of these examinations to say the least complex must be made and the results should be compared to other symptoms before drawing conclusions. Other blood tests as well as additional examinations - MRI, ultrasound of the liver and bile ducts - must be carried out.
Another type of liver function test is prothrombin time which was made for calculating the international normalized ratio. In a situation where this test seems abnormal, it signifies that there is an acute disorder in liver.