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Alzheimer's Disease: Ultrasound To The Rescue Of The Brain

There are about 50 million people worldwide who suffer from Alzheimer's disease. This number, which will increase even more with the increase in the elderly population, has made Alzheimer's disease one of the biggest health problems of our time. There is no definitive cure for the disease currently known. With the drugs we have, we can only slow the course of the disease.

rescue-of-the-brain

Alzheimer's disease results from a slow degeneration of neurons, starting in the hippocampus (a brain structure essential for memory) and then spreading to the rest of the brain. It is characterized by recent memory disorders, executive functions, and orientation in time and space. The patient gradually loses his cognitive faculties and his autonomy.

It is characterized by neurological degeneration which affects cognitive capacities, including memory. If drugs can slow this process down, the disease is still incurable.

But research continues to open up avenues. The ultrasound technique already being tested for brain tumors could also help Alzheimer's patients. Since the brain is a very "tight" organ, chemotherapy has great difficulty in penetrating it, but ultrasound has the property of making it more permeable and of facilitating the access of the chemo to the tumor. Patients are currently in clinical trials, and the method is so promising that it will soon also be tested in the treatment of Alzheimer's disease.

What if we could treat Alzheimer's disease or brain tumors more effectively?

The blood-brain barrier is a kind of physiological shield all around the brain. Its mission is to prevent possible toxins from entering it. A protective barrier which also complicates the treatment of neurological diseases since therapeutic fluids, drugs cannot or very little cross it.

Alzheimer's disease, sometimes considered the disease of the century, could be cured thanks to an extraordinarily promising new technique using ultrasound to remove aggregates of toxic proteins suspected of causing this famous disease as well as dementia. A treatment that has proven itself in animal tests.

The ultrasound test technique is exceptional in that it opens this shield and therefore makes the barrier permeable. We now know that this makes it possible to better distribute chemotherapy in the brain. Originally, a discovery that creates real hope in the treatment of previously incurable brain tumors. Treatment can be greatly improved, thanks to the opening of the blood-brain barrier.

Experts have developed an ultrasound system that opens these previously waterproof vessels and make chemotherapy easier to penetrate. The molecule directly reaches its goal and it heals better.

It would be a healthy way, without medication and without any harm to the sick, to heal. Initially, the research aimed to find a way to use ultrasound to temporarily open the blood-brain barrier to help dementia-fighting antibodies better reach their target in the brain.

Ultrasound waves oscillate rapidly, activating microglial cells, destroying amyloid plaques that destroy neuron synapses in these cells. This approach activates the memory-repairing mechanism by temporarily opening the blood-brain barrier, clearing toxic protein clumps.

Since these initial observations, the team has decided to work to refine its technique. They have successfully proven that the treatment removes toxic proteins and safely restores memory. Experts suggests that if you are going to have an ultrasound, it is better to know ultrasound price in Delhi first.

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